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Research··1 min read

Freezing threatens mRNA delivery, but Tris buffer helps nanoparticles retain their potency

Researchers from The University of Texas at Austin and Eli Lilly have found that freezing can damage mRNA lipid nanoparticles used in vaccines, but using Tris buffer helps maintain their effectiveness. This discovery could improve storage methods for these crucial treatments.

Freezing threatens mRNA delivery, but Tris buffer helps nanoparticles retain their potency
Image: Phys.org

Researchers from The University of Texas at Austin and Eli Lilly have found that freezing can damage mRNA lipid nanoparticles used in vaccines, but using Tris buffer helps maintain their effectiveness. This discovery could improve storage methods for these crucial treatments.

Sources

  • Phys.org — Freezing threatens mRNA delivery, but Tris buffer helps nanoparticles retain their potency

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