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Science··1 min read

Computer-designed protein targets immune receptor linked to inflammation at new 'undruggable' site

Scientists have designed a protein that targets Toll-like receptor 4 (TLR4), an immune receptor linked to inflammatory disorders such as sepsis and arthritis. Despite its importance, TLR4 has been challenging to target with drugs, but this new design could open up new therapeutic possibilities.

Computer-designed protein targets immune receptor linked to inflammation at new 'undruggable' site
Image: Phys.org

Scientists have designed a protein that targets Toll-like receptor 4 (TLR4), an immune receptor linked to inflammatory disorders such as sepsis and arthritis. Despite its importance, TLR4 has been challenging to target with drugs, but this new design could open up new therapeutic possibilities.

Sources

  • Phys.org — Computer-designed protein targets immune receptor linked to inflammation at new 'undruggable' site

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